BioCeuticals Ubiquinol BioActive 300mg provides the highest dose of ubiquinol per capsule available on the Australian market, being first to market again.
Ubiquinol is the reduced (active) form of coenzyme Q10 with superior absorption and higher bioavailability than other forms of CoQ10.
Each capsule contains:
Ubiquinol-10 (reduced coenzyme Q10) 300 mg
Adults: Take 1 capsule once daily or as directed by your healthcare practitioner.
Do not take while on Warfarin therapy without medical advice.
Although generally well tolerated, the use of ubiquinol in pregnancy and lactation has not been scientifically validated.
Statin drugs are known to adversely affect CoQ10 levels by inhibiting the enzyme HMG-CoA reductase required for the synthesis of cholesterol in the liver as well as for CoQ10 production.
CoQ10 has shown promise as an effective prophylactic for migraine headaches. Trials administering 150-300mg CoQ10 per day have found reduced migraine attack frequency, reduced number of days with migraine headache and a reduced number of days with nausea.
The efficacy of CoQ10 supplementation increased as the trials progressed, with the most significant improvements occurring after three months of treatment. The efficacy of CoQ10 in preventing migraine headaches may be attributed to its ability to improve mitochondrial dysfunction and oxygen metabolism, both of which may contribute to migraine pathogenesis.
Overproduction of free radicals or reactive oxygen species (ROS) is associated with sperm destruction and infertility. Several clinical trials have investigated the effects of ubiquinol on sperm health and found that it may provide antioxidant support and maintain healthy sperm motility and morphology.
Clinical trials utilising 200mg of ubiquinol for six months in men with unexplained subfertility found that it improved parameters of sperm health including density, motility and morphology. The mechanisms behind these improvements include increasing seminal CoQ10 levels, improving antioxidant defences and reducing spermatozoal oxidative stress (SOS).
The highest concentrations of CoQ10 are found in the heart, with ageing, hypertension, heart failure and statin-treated patients showing evidence of CoQ10 deficiency.
CoQ10 plays an important role in energy production in muscle cells, with concentrations of CoQ10 declining with intense athletic training.
Research shows that ubiquinol may improve athletic performance and physical power production. Supplementation with 300mg ubiquinol for six weeks has shown to significantly enhance physical performance in trained athletes, compared to placebo.
Reduced fatigue and enhanced performance has also been demonstrated in trials utilising 100-300mg CoQ10 per day in both trained and untrained individuals.