GABA Mood Assist¶? features PharmaGABA¶©. This natural form of GABA may help assist symptoms of stress, mood disorders and insomnia.
What is GABA?
GABA or gamma-aminobutyric acid is the most important inhibitory neurotransmitter and is widely distributed throughout the central nervous system (CNS).Within the CNS glutamic acid, a non-essential amino acid is converted to GABA via glutamate decarboxylase and the co-factor pyridoxal 5′ phosphate (P5P). GABA is often referred to as the ¶?calming’ neurotransmitter. Endogenous GABA plays a key role in neuronal inhibition to act as a ¶?brake’ during times of runaway stress .
GABA regulates CNS excitability via GABA receptors. These receptors are classified into three major groups (alpha, beta and gamma). Alpha, beta and gamma waves are key indicators of brain activity. Alpha waves are generated when an individual is relaxed, yet alert. In contrast, low amplitude beta waves increase in stressful situations and make mental concentration difficult. In general, a greater alpha-to-beta ratio is associated with a more relaxed and alert state. GABA activates greater alpha wave activity.
In healthy individuals the CNS is capable of producing sufficient GABA but due to a variety of environmental or health reasons the levels can fall. Imbalances in GABA concentrations may be associated with increased nervousness and anxiety. The widely prescribed anti-anxiety medications target GABA activity.
About GABA Mood Assist¶?
Stress & Mild Anxiety
- GABA Mood Assist¶? may help relieve nervous tension, stress and mild anxiety.
One study investigated the effects of orally administrated PharmaGABA¶© on alpha and beta waves of the CNS in healthy subjects as well as measuring salivary IgA levels during times of stress. Based on the results 100mg of PharmaGABA¶© led to a significant increase in alpha waves and a decrease in beta waves compared to the control group.
Secretory immunoglobulin A (IgA) has been suggested to play an important role in protecting the respiratory tract from infection. Typically, during times of stress and anxiety salivary IgA levels drop. In this study subjects with acrophobia traversed a walking suspension bridge that spanned a 54 metre high canyon. Salivary IgA levels decreased when subjects were given a placebo; however when they were given PharmaGABA¶© salivary IgA levels were higher at the bridge end. The results demonstrated that PharmaGABA¶©administration may increase IgA levels even in stressful conditions.
- Chronic insomnia is common and often associated with long term health problems such as obesity, hypertension and mood disorders.
Insomnia peaks from 45-64 years of age and a second increase appears in people 85 and older. Further, insomnia is especially common during peri-menopause and is strongly associated with the use of sleeping medications which can have adverse effects.
GABA Mood Assist¶? may be considered a natural sleep aid to support the relief of insomnia. GABA Mood Assist¶? is non-addictive and does not result in daytime drowsiness.
What is PharmaGABA¶©?
- PharmaGABA¶© is a naturally produced form of GABA that may deliver superior clinical results compared to synthetic forms. PharmaGABA¶© is a highly bioactive and concentrated form of GABA. It is made from glutamic acid which is produced from the fermentation process of lactobacillus hilgardii. This beneficial bacteria is normally used to ferment vegetables in the preparation of the traditional Korean dish known as kimchi.
- GABA Mood Assist¶? featuring PharmaGABA¶© may help promote natural relaxation while assisting mental focus.
- Dr. Michael T. Mur(ray, ND who is widely regarded as an authority on natural medicine recommends PharmaGABA¶© as a safe alternative for feelings of stress and anxiety .
Each Vegetable Capsules (Vcap¶©) Contains
Gamma-aminobutyric acid (PharmaGABA¶© 80) 100mg
Contains no gluten, soy, dairy, yeast, wheat, animal products, artificial flavours, colours or preservatives.
Directions For Use
Adults: Take 1 Vcap¶© 1 to 3 times a day away from meals or as directed by your healthcare practitioner.
To assist insomnia: Take 1 to 2 Vcaps¶© one hour before bedtime.
As a general guideline no more than 600mg of GABA Mood Assist¶? should be taken in a six hour time period.
Children (12 years and older): Take 1 Vcap¶© 1 to 3 times a day away from meals or as directed by your healthcare practitioner.
- Not recommended in pregnancy or lactation. PharmaGABA¶© has not been studied in pregnancy or lactation.
- Not suitable for individuals with diagnosed clinical depression or bipolar disorders.
Precautions & Considerations
- Does not cause drowsiness and is non-habit forming.
- If symptoms persist consult your healthcare practitioner.
- The blood brain barrier is a complex regulatory system that includes various efflux transport mechanisms to regulate GABA levels. There is a limited capacity of the CNS to retain excessive concentrations of GABA .
PharmaGABA¶© is a trademark of Pharma Foods International Co., Ltd. (Japan)