RN Labs L-5MTHF 120c


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RN Labs L-5MTHF is a pure and highly bioavailable form of folate.

Directly facilitating methyl group donation in the body, L-5MTHF may support numerous metabolic processes for optimum healing, development, detoxification, mental health and wellbeing.

  • Provides a methylated and metabolically active form of folate
  • May bypasse the biochemical steps normally required by other folates
  • Demonstrates greater metabolic activity than folic acid as a source of folate, with reduced potential for side effects
  • May contribute to the normal growth of the foetus during pregnancy
  • May support normal stress and cognitive function through healthy neurotransmitter production
  • May support healthy red blood cell formation
  • May play an important role in supporting healthy methylation
  • May support healthy homocysteine levels
  • May support healthy cardiovascular and vascular endothelial function

Each vegetarian capsule contains:

Calcium L-5-methyltetrahydrofolate


     Equiv. Levomefolic acid (L-5-MTHF)


Excipients: Leucine, Tapioca Starch, Microcrystalline Cellulose, Colloidal Anhydrous Silica

For Practitioner Dispensing Only
If symptoms persist consult your healthcare practitioner.
Vitamin supplements should not replace a balanced diet.
Folate is considered safe during pregnancy.

Known Side Effects
In doses typically administered for therapeutic purposes, 5-MTHF is considered non-toxic. At doses over 10mg daily, gastrointestinal complaints, insomnia, irritability, and fatigue have been reported.
Whilst some concern exists that supplementation with high doses of folic acid could mask a vitamin B12 deficiency, supplementation with 5-MTHF appears to sidestep this potential problem. Since 5-MTHF can only be converted to 5,10-methylenetetrahydrofolate (involved in DNA synthesis) after participating in homocysteine recycling with vitamin B12, 5-MTHF will not mask a B12 deficiency.

Medication Interactions
The activity of 5-MTHF may affect, or be affected by, the presence of certain medications, including anticonvulsant and anti-inflammatory medications. Qualified consultation is advised when using these concomitantly.
TGA Listed product with Aust L 394270.

 Download TGA Public Summary for TGA published information including excipients, which are listed under 'Other Ingredients'.