ChinaMed Menopause 2 Formula 78c

Description

This is an empirical formula that is based on a combination of three formulas: Er Xian Tang (Formula of the Two 'Xian' Herbs a.k.a. Epimedium & Curculigo Combination), Bai He Di Huang Tang and Gan Mai Da zao Tang (Licorice, Wheat and Jujube Combination). The former is a relatively modern formulation that may support hypertension in menopause. Not only was it shown to be effective for this, but it may also have the side effect of reducing hot flushes. The latter formula was first recorded over 2,000 years ago in the Synopsis of Prescriptions of the Golden Chamber (jin gui yao lue fang lun), by Zhang Zhongjing (circa 150 ‐ 219 A.D). It was originally used for 'restless organ' (zang zao) disorder, which was classified under the heading of gynecological disorders. The main symptoms are dysphoria and overwhelming or uncontrollable emotional responses. Bai He Di Huang ang, also from the same classic text, may clear Heat, cool the Blood and calm the Spirit, which may help alleviate hot flushes, anxiety and irritability.

This formula may benefit women in the perimenopausal period, who present with frequent hot flushes with sleep disturbance, irritability and emotional volatility. The pathogenesis of hot flushes in menopause is complex and may include: Kidney Yin deficiency, Kidney Yang deficiency, Kidney Qi deficiency and Spleen Qi deficiency. The first syndrome leads to Yang hyperactivity, whereas the latter three may lead to 'stirring' of the Minister Fire (the Fire of the Life Gate), which is normally stored in the lower Jiao. In many cases, several of these syndromes may occur concurrently. This formula may address hot flushes due to Kidney Yang deficiency or Kidney Qi deficiency together with the Fire that may arise as a consequence. Therefore in cases with marked Kidney Yin deficiency, it is best combined with specific Kidney Yin tonifying formulas as described above.


TCM ACTIONS
Nourishes the Kidney and Liver, reduces deficiency Fire, nourishes the Heart Blood, settles the Yang to calm the Spirit.

TCM SYNDROMES
Deficiency of the Kidney and Liver with deficiency Fire
Heart Blood deficiency

INDICATIONS
Menopausal syndrome with hot flushes.

SIGNS & SYMPTOMS (Key clinical features in bold)

• Hot flushes due to menopause
• Irritability
• Night sweats
• Cold hands and feet
• Sleep disturbance

Each 300 mg capsule contains extract equiv. to dry:
Triticum aestivum, seed (fu xiao mai)	397.8mg
Rehmannia glutinosa, root (di huang)	198mg
Ziziphus jujuba, fruit (da zao)	133.2mg
Lilium brownii, bulb (bai he)	133.2mg
Albizia julibrissin, stem bark (he huan pi)	118.8mg
Epimedium sagittatum, herb (yin yang huo)	118.8mg
Curculigo orchioides, rhiz. (xian mao)	118.8mg
Lycium barbarum, fruit (gou qi zi)	118.8mg
Eucommia ulmoides, stem bark (du zhong)	118.8mg
Loranthus parasiticus, stem (sang ji sheng)	118.8mg
Morinda officinalis, root (ba ji tian)	79.2mg
Chrysanthemum sinense, flower (ju hua)	79.2mg
Glycyrrhiza uralensis, root (zhi gan cao)	66.6mg

• Do not take within 90 minutes of taking antibiotics.
• Contains Glycyrrhiza, which potentiates prednisone and corticosteroids by prolonging steroid biological half-life; caution in patients with hypertension.
• Contains gluten. Not to be used in cases with allergy to gluten.

TGA Listed product with Aust L 342366.

 Download TGA Public Summary for TGA published information including excipients, which are listed under 'Other Ingredients'.